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Diazepam is N-demethylated by CYP3A4 and 2C19 towards the Energetic metabolite N-desmethyldiazepam, and it is hydroxylated by CYP3A4 for the active metabolite temazepam. N-desmethyldiazepam and temazepam are the two more metabolized to oxazepam. Temazepam and oxazepam are mainly removed by glucuronidation. You will find there's pregnancy registry

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